A 28-year-old woman with a history of tendon disorders with quinolone use. Which antibiotic is contraindicated?

A 28-year-old woman with a history of tendon disorders with quinolone use. Which antibiotic is contraindicated?

• A. Ciprofloxacin
• B. Amoxicillin
• C. Levofloxacin
• D. Doxycycline

Answer: (C)

Fluoroquinolones carry a well-known risk of tendon injury, including tendinopathy and tendon rupture. This risk is especially concerning in patients who have had tendon disorders after quinolone exposure. In a patient with a history of quinolone-associated tendon problems, re-exposure to this antibiotic class is contraindicated. Among the options, the drugs in the fluoroquinolone family should be avoided, while non-quinolone antibiotics such as amoxicillin or doxycycline do not carry this specific tendon risk and can be considered based on the infection. So, the antibiotic class contraindicated here is the fluoroquinolone one.

Fluoroquinolones carry a well-known risk of tendon injury, including tendinopathy and tendon rupture. This risk is especially concerning in patients who have had tendon disorders after quinolone exposure. In a patient with a history of quinolone-associated tendon problems, re-exposure to this antibiotic class is contraindicated. Among the options, the drugs in the fluoroquinolone family should be avoided, while non-quinolone antibiotics such as amoxicillin or doxycycline do not carry this specific tendon risk and can be considered based on the infection. So, the antibiotic class contraindicated here is the fluoroquinolone one.